Ceramides: What they are, what they do, and how Ceramosides HP can help you

June 24, 2021

What are ceramides?

In the beauty world, ceramides are a necessity of the market, but why? It’s because they are the principal of the multilamellar lipid barrier of the skin, along with cholesterol and saturated fatty acids. Basically, it keeps the skin hydrated and protected against drying and irritation. They are made of a sphingoid base (C18-20), a fatty acid (C16-36) and an amide linkage between them! [1]

Ceramide structure [2]

While ceramides are naturally in the skin, over time the levels decrease. This means that alternative ways of introducing ceramides to the skin is necessary to avoid dryness and irritation!

What are the different types?

What many people do not know is that the ceramides added to certain products actually vary!
They differ from each other in the nature of the sphingoid base (sphingosine, phytosphingosine,...) and in the length and hydroxylation (position of the -OH groups) of the carbon chain of fatty acids.

Up to nine different ceramides have been identified in the skin, and ceramides 2 (21%), 3 (13%), 5 (18%) and 8 (22%) are mainly found in stratum corneum. [3]

Ceramide 3 (NP) and ceramide 4 (EOH) and long-chain ceramides with 18–26 carbons are known to be the major components of the epidermal barrier, and along with ceramide 1 (EOS), are known to be essential components in creating the lamellar structure of the epidermal barrier, to prevent water loss. [4] They are perfect for body lotions, butters, or any product with ceramides that targets dryness.

Some studies have shown that short chain ceramides might on the contrary increase SC permeability, while increasing ceramides differentiation (especially the C6 acyl chain). [5] [6]


Which ingredients help restore ceramide levels?

While many products include ceramides, there is an option that has a better affinity with the skin! Ceramosides™ HP is a glucolipidic extract that, compared to ceramides, is more efficient thanks to its polarity.

The polar lipids are extracted from non GMO wheat from France, proteins are removed to make it a gluten-free ingredient with more than 77% Omega 3, 6 and 9. CERAMOSIDES HP contains:

  • a high concentration of glucosylceramides (Glycosphingolipids), similar to the skin’s ceramides 2, 3 & 8.
  • Glycolipids (Digalactosyl Diglyceride), very amphiphilic, making the ceramide fraction more hydrophilic and better absorbed

100% natural, gluten-free, non-GMO, and COSMOS approved, Ceramosides HP is a biomimetic complex that protects the skin from premature aging due to environmental stresses, moisturizes the skin and helps to tight pores and visibly refine complexions.

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References: [1] Luisa Coderch &Al. Ceramides and skin function. Online:

[2] Basic chemical structure of ceramides (Cha et al., 2016)

[3](Coderch et al., 2003).

[4] Cha, H. J., He, C., Zhao, H., Dong, Y., An, I., An, S."Intercellular and intracellular functions of ceramides and their metabolites in skin (Review)". International Journal of Molecular Medicine 38, no. 1 (2016): 16-22.

[5] Robert Baran, Howard Maibach. Textbook of Cosmetic Dermatology

[6] Pillai S, Cho S, Mahajan M, Frew L, Rawlings AV. Synergy between vitamin D precursor 25-hydroxyvitamin D and short chain ceramides on keratinocyte proliferation and differentiation. The Journal of Investigative dermatology. Symposium Proceedings. 1996 Apr;1(1):39-43.