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NEW DATA! A procollagen boost with ASPAR’AGE™

May 16, 2019

A young and healthy skin is made of 75 to 80% of collagen, a protein located in the dermis and providing strength and support to the skin and produced by the fibroblasts cells. It also has a high water-binding capacity, and contributes to a moisturized, smooth and supple skin. Unfortunately, collagen production slows down with age. ASPAR’ AGE™ (opens new window), our active ingredient reducing contagious aging in the skin, was the perfect candidate for a collagen boosts!

Collagens_in_the_skin

New test: Procollagen I boost

The pro-collagen is a precursor of collagen, made of amino acid chains organized in triple helix.

Collagen_synthesis

In vitro, ASPAR'AGE™ (opens new window) showed a significant increase of procollagen type 1 secretion by fibroblasts vs the control. It boosts the collagen precursors amount in the skin for a younger look!

The ingredient: a red algae extract rich in Mycosporine-like aminoacids

ASPAR'AGE™ (opens new window) is extracted from the red algae Asparagopsis armata, an algae rich in mycosporine-like amino acids (MAAs), small metabolites providing UV protection to the algae.

asparagopsis

Eaten by Sea Hares, cousins of sea slugs and octopuses, the MAAs of the algae provides to the animal the ability to repel predators, alarms each other of a danger,... It is the key molecule for their survival and communication. And it also affects the survival and communication between cells in our skin…

An innovative mechanism: reduction of the contagious aging

Aging generates senescent cells, unable to duplicate and divide anymore. These “tired” cells release numerous molecules, the “Senescence messaging secretome” (SMS), which will affect neighbouring young cells and induce “contagious aging”. Seppic developed a new in vitro and patented model to show that ASPAR'AGE™ (opens new window) is able to protect young fibroblasts from this contagious aging, in order to preserve the skin’s youth capital.

The results: measurable and visible results

After 28 days treatment, at 2%, clinical results showed a reduction of the under eye wrinkles.

under_eye

But what matters the most for consumers is visible results. The pictures of each volunteer were taken at D0 and D28, and were all compared by a large naive panel.
Panelists were able to find the “after treatment” pictures, and saw a younger look, less wrinkled. ASPAR'AGE™ (opens new window) contributes to improve the skin appearance, by protecting from contagious aging.

A natural and efficient active

INCI: Glycerin - Aqua / Water - Propanediol - Asparagopsis Armata Extract
Use level: 2%
Approvals: China compliant, ECOCERT, COSMOS

Questions, samples? Ask us in the chat!